An Introduction to Medicinal Chemistry
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Product details:
- Edition number 7
- Publisher OUP Oxford
- Date of Publication 16 March 2023
- ISBN 9780198866664
- Binding Paperback
- No. of pages960 pages
- Size 280x219x36 mm
- Weight 2336 g
- Language English 796
Categories
Short description:
The market-leader in medicinal chemistry: clear, supportive, and practical. It helps students to effortlessly make the link from theory to real-life applications using practical and focused coverage alongside a package of supportive online resources.
MoreLong description:
Medication is widely used to support the human body to fight against infection and pain. In an era of pharmaceutical and medicinal challenges, we have all become more familiar with drug production and distribution. However, do we really know what happens before those drugs are distributed? What's the process behind drug discovery? How do our bodies interact with those chemicals?
An Introduction to Medicinal Chemistry, 7th edition, offers a complete and accessible approach to this multidisciplinary field. Its student-friendly writing style makes this text an ideal tool for those coming to the subject for first time, but also for students looking to deepen their understanding.
The book guides students through understanding the principles of drug action targets in Part A, to how drugs interact at a molecular level with our organs to offer therapeutic value in Part B, and exploring drug design and discovery, as well as regulatory procedures in Part C. Offering a practical approach, Part D provides a deeper look at specific tools and techniques of medicinal chemistry, concluding with emerging topics including antibodies and anticancer agents in Part E.
From principles to practice, accompanied by examples and case studies emerging from current biomedical research, the book will equip students with a robust understanding of medicinal chemistry, to prepare them for future success.
The best general undergraduate textbook on medicinal chemistry. This new edition retains the accessible style of writing, but provides important updates on the topics.
Table of Contents:
Drugs and Drug Targets
Protein Structure and Function
Enzymes: Structure and Function
Receptors: Structure and Function
Receptors and Signal Transduction
Nucleic Acids: Structure and Function
Enzymes as Drug Targets
Receptors as Drug Targets
Nucleic Acids as Drug Targets
Miscellaneous Drug Targets
Pharmacokinetics and Related Topics
Statins
Drug Discovery: Finding a Lead
Drug Design: Optimizing Target Interactions
Drug Design: Optimizing Access to the Target
Getting the Drug to Market
The Design of ACE Inhibitors
Artemisinin and Related Antimalarial Drugs
The Design of Oxamni
Fosfidomycin as an Antimalarial Agent
Combinatorial and Parallel Synthesis
In Silico Drug Design
Quantitative Structure-Activity Relationships
De Novo Design of a Thymidylate Synthase Inhibitor
Antibacterial Agents
Antiviral Agents
Anticancer Agents
Protein Kinase Inhibitors as Anticancer Agents
Antibodies and Other Biologics
Cholinergics, Anticholinergics, and Anticholinestarases
Drugs Acting on the Adrenergic Nervous System
The Opioid Analgesics
Anti-Ulcer Agents
Cardiovascular Drugs
Steroidal Anti-Inflammatory Agents
Design of a Novel Antidepressant
The Design and Development Of Aliskiren
Factor Xa Inhibitors
Reversible Inhibitors of HCV NS-34A Protease
