Long description:

Animal Models of Disease, Part B, Volume 188 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Using C. Elegans as a model for Neurodegenerative disease: Methodology and Evaluation, Modelo Animal de Esclerosis Multiple: Encefalomielitis Autoimmune Experimental (EAE, New mouse model to study aneurysm development, Spinal Nerve Ligation: An Experimental Neuropathic Pain Model in Rats and Mice, Identifying therapeutic compounds for Autosomal Dominant Optic Atrophy (ADOA) through screening in the nematode C. elegans, Eµ-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia, and much more.

Other chapters cover Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis, Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models, Assessing motor development and function in mouse models of neurodevelopmental disorders, Analysis of Gut Microbiota profile targeted to multi hypervariable regions of 16S rRNA in hypertensive heart failure rat model, and more.

Table of Contents:

Preface
Lorenzo Galluzzi, Fernando Aranda Vega, Aitziber Buque Martinez and Jose Manuel Bravo-San Pedro

1. Using C. elegans as a model for neurodegenerative diseases: Methodology and evaluation
Elena Caldero-Escudero, Silvia Romero-Sanz and Sergio De la Fuente

2. Animal model of multiple sclerosis: Experimental autoimmune encephalomyelitis
Ana Mu?oz-Jurado, Bego?a Escribano and Isaac Túnez

3. A new procedure to induce aortic aneurysms in mice
Raquel Rodrigues-Díez, Antonio Tejera-Mu?oz and Raúl R. Rodrigues-Diez

4. Spinal nerve ligation: An experimental model to study neuropathic pain in rats and mice
Erick J. Rodríguez-Palma, Itzel I. Ramos-Rodríguez, Saúl Huerta de la Cruz, Vinicio Granados-Soto and Maria Sancho

5. Identifying therapeutic compounds for autosomal dominant optic atrophy (ADOA) through screening in the nematode C. elegans
Fivos Borbolis and Konstantinos Palikaras

6. E?-TCL1 adoptive transfer mouse model of chronic lymphocytic leukemia
Iria Fernandez Botana, Susanne Gonder, Vanessa Klapp, Etienne Moussay and Jerome Paggetti

7. Purification and characterization of kidney-infiltrating leukocytes in a mouse model of lupus nephritis
Laura Amo, Hemanta K. Kole, Bethany Scott, Francisco Borrego, Chen-Feng Qi,
Hongsheng Wang and Silvia Bolland

8. Differences in intratumor innate lymphoid cell composition between orthotopic and spontaneous pancreatic mouse models
Sara Lamorte, Alisha R. Elford, Douglas C. Chung, Kiichi Murakami, Tracy L. McGaha and Nicolas Jacquelot

9. Assessing motor development and function in mouse models of neurodevelopmental disorders
Lauren Dierdorff, Marta Garcia-Forn, Alexa von Mueffling and Silvia De Rubeis

10. Analysis of the gut microbiota profile targeted to multiple hypervariable regions of 16S rRNA in a hypertensive heart failure rat model
Javier Modrego, Adriana Ortega-Hernández, Silvia Sánchez-González, Arturo Corbatón-Anchuelo and Dulcenombre Gómez-Garre

11. Animal models of neglected parasitic diseases: In vivo multimodal imaging of experimental trypanosomatid infections
Jean Marc Tsagmo Ngoune, Brice Rotureau and Estefanía Calvo Alvarez

12. Intracranial graft of bioresorbable polymer scaffolds loaded with human dental pulp stem cells in stab wound murine injury model
Irene Manero-Roig, Yurena Polo, Beatriz Pardo-Rodríguez, Jon Luzuriaga, Ruth Basanta-Torres, Daniel Martín-Aragón, Irene Romayor, Sara Martín-Colomo, Joana Márquez, Laura Gomez-Santos, Frédéric Lanore, Yann Humeau, Gaskon Ibarretxe, Cristina Eguizabal,
Aitor Larra?aga and Jose Ramon Pineda