Carcinogen-Driven Mouse Models of Oncogenesis
Series: Methods in Cell Biology; 163;
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Product details:
- Publisher Academic Press
- Date of Publication 26 March 2021
- ISBN 9780128225349
- Binding Hardback
- No. of pages256 pages
- Size 235x191 mm
- Weight 790 g
- Language English 198
Categories
Long description:
Carcinogen-Driven Mouse Models of Oncogenesis, Volume 163 contains a series of protocols written by world-leading experts in the field. Each manuscript provides a detailed methodological description to drive carcinogen-mediated oncogenesis in mice. Chapters in this new release include Chemical carcinogenesis in mice as a model of human cancer: Pros and cons, MPA/DMBA-driven mammary carcinomas, Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice, Urethane-induced lung carcinogenesis, Methylcholanthrene-induced fibrosarcomas, BBN-driven bladder carcinomas, Oral squamous cell carcinomas driven by 4NQO, Analyzing skin tumor development in mice by the DMBA/TPA model, and much more.
Other sections cover DSS/AOM-driven colorectal carcinomas, Diethylnitrosamine-induced liver tumorigenesis in mice, Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice, Lung carcinomas induced by NNK and LPS, Pristane-induced mammary carcinomas, The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis, and more.
- Provides protocols provided by renowned experts in the field
- Presents detailed descriptions of protocols, hence allowing appropriate reproduction of the models
- Includes author notes for each protocol, covering useful tips and troubleshooting
Table of Contents:
1. Preface - Chemical carcinogenesis in mice as a model of human cancer: Pros and cons
Lorenzo Galluzzi
2. MPA/DMBA-driven mammary carcinomas
Aitziber Buqué Martinez
3. Dimethylbenz(a)anthracene-Induced Mammary Tumorigenesis in mice
Isabelle Plante
4. Urethane-induced lung carcinogenesis
Silvano Sozzani
5. Methylcholanthrene-induced fibrosarcomas
Awen Gallimore
6. BBN-driven bladder carcinomas
Janos Terzic
7. Oral squamous cell carcinomas driven by 4NQO
Nancy J. Philp
8. Analysing skin tumor development in mice by the DMBA/TPA model
Cord Brakebusch
9. DSS/AOM-driven colorectal carcinomas
David C. Montrose
10. Diethylnitrosamine-induced liver tumorigenesis in mice
Peter Hasselblatt
11. Two-stage 3-methylcholanthrene and butylated hydroxytoluene-induced lung carcinogenesis in mice
Alison K. Bauer
12. Lung carcinomas induced by NNK and LPS
Peter Di
13. Pristane-induced mammary carcinomas
Bae Hoon Lee
14. The 4-NQO mouse model: an update on a well-established in vivo model of oral carcinogenesis
Pierre Saintigny
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