Hypoxia in Cancer: Significance and Impact on Cancer Therapy
- Publisher's listprice EUR 213.99
-
90 774 Ft (86 451 Ft + 5% VAT)
The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.
- Discount 8% (cc. 7 262 Ft off)
- Discounted price 83 512 Ft (79 535 Ft + 5% VAT)
90 774 Ft
Availability
Estimated delivery time: In stock at the publisher, but not at Prospero's office. Delivery time approx. 3-5 weeks.
Not in stock at Prospero.
Why don't you give exact delivery time?
Delivery time is estimated on our previous experiences. We give estimations only, because we order from outside Hungary, and the delivery time mainly depends on how quickly the publisher supplies the book. Faster or slower deliveries both happen, but we do our best to supply as quickly as possible.
Product details:
- Edition number 2023
- Publisher Springer
- Date of Publication 16 April 2024
- Number of Volumes 1 pieces, Book
- ISBN 9789819903153
- Binding Paperback
- No. of pages447 pages
- Size 235x155 mm
- Language English
- Illustrations 1 Illustrations, black & white 613
Categories
Short description:
This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
MoreLong description:
This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and treatment of cancer. The book provides an overview of hypoxia imaging, its biological relevance, and mechanism of action. It helps in understanding the molecular mechanisms of the regulation of senescence by hypoxia. It explores the contribution of hypoxia to immune resistance and immune suppression/tolerance and determines the hypoxia-responsive long non-coding RNAs in regulating hypoxic gene expression at chromatin, transcriptional, and post-transcriptional levels. Further, it presents the functional link between hypoxia and miRNA expressions and hypoxia-regulated miRNAs in cancer cell survival in a low oxygen environment. Lastly, it discusses the applications of tumor-on-a-chip technology for the understanding of hypoxia-tumor microenvironment. This book is a valuable source for oncologists and scientists working to understand the role of hypoxia in cancer and therapeutic approaches.
MoreTable of Contents:
Chapter 1. Hypoxia and its Biological Implications for Cancer Therapy.- Chapter 2. Hypoxia's function in cancer.- Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology.- Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression.- Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression.- Chapter 6. Hypoxia Regulated Gene Expression and Metastasis.- Chapter 7. piRNA based cancer therapy in hypoxic tumor.- Chapter 8. MicroRNA Signatures of Tumor Hypoxia.- Chapter 9. Hypoxia and the Metastatic Cascade.- Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis.- Chapter 11. Role of Hypoxia in Cancer Therapy ? Introduction.- Chapter 12. Hypoxic regulation of telomerase gene expression in cancer.- Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia.- Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment.- Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models.- Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights.- Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia.- Chapter 18. Hypoxia Induced Apoptosis in Cancer Development.- Chapter 19. Hypoxia in drug resistance and radioresistance.
Arch?: A Collection of Patristic Studies
100 959 HUF
Minimalism
14 145 HUF
Paul Dukas: Legacies of a French Musician
73 384 HUF
Dearly: New Poems
10 874 HUF
Fight for Life
3 104 HUF
