Optical Polarimetric Modalities for Biomedical Research
Series: Biological and Medical Physics, Biomedical Engineering;
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Product details:
- Edition number 2023
- Publisher Springer
- Date of Publication 26 July 2023
- Number of Volumes 1 pieces, Book
- ISBN 9783031318511
- Binding Hardback
- No. of pages452 pages
- Size 235x155 mm
- Weight 857 g
- Language English
- Illustrations 8 Illustrations, black & white; 130 Illustrations, color 540
Categories
Short description:
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.
MoreLong description:
This book focuses on polarization microscopy, a powerful optical tool used to study anisotropic properties in biomolecules, and its enormous potential to improve diagnostic tools for various biomedical research. The interaction of polarized light with normal and abnormal regions of tissue reveals structural information associated with its pathological condition. Diagnosis using conventional microscopy can be time-consuming, as pathologists require an hour to freeze and stain tissue slices from suspected patients. In comparison, polarization microscopy more quickly distinguishes abnormal tissue and provides better microstructural information of samples, even in the absence of staining. This book provides a basic understanding of the properties of polarized light, a description of the polarization microscope, and a mathematical formalism of Mueller matrix polarimetry. The authors discuss various advanced linear and nonlinear optical techniques such as optical coherence tomography (OCT), reflectance and transmission spectroscopy, fluorescence, multiphoton excitation, second harmonic generation, Raman microscopy, and more. They explore the exciting potential of integrating polarimetry with these techniques for possible applications in different areas of biomedical research, as well as the associated challenges. Including the most recent developments on the topic, this book serves as a modern guide to polarization microscopy and advancements in its use in biomedical research.
MoreTable of Contents:
PartI. Stokes Mueller based polarimetry.- Chapter1. Polarization imaging of optical anisotropy in soft tissues.- Chapter2. Polarization techniques in biological microscopy.- Chapter3. Stokes Mueller Matrix Polarimetry: Effective Parameters of Anisotropic Turbid Media - Theory and Application.- Chapter4. Mueller matrix imaging.- Chapter5. Biological imaging through optical Mueller-matrix scanning microscopy.- Chapter6. Mueller polarimetry for biomedical applications.- Chapter7. Scattering phase functions and polarimetric responses of selected bioparticles.- PartII. Nonlinear polarization microscopy.- Chapter8. Polarization resolved nonlinear optical microscopy.- Chapter9. Polarization-resolved SHG microscopy for biomedical applications.- Chapter10. Polarization-resolved second harmonic generation for tissue imaging.- PartIII. Applications of polarization techniques.- Chapter11. An Introduction to Fundamentals of Cancer Biology.- Chapter12. Polarization enabled optical spectroscopy and microscopy techniques for cancer diagnosis.- Chapter13. Polarization Microscopy in Biomedical Applications.- Chapter14. Machine learning in tissue polarimetry.
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