
Pharmaceutical Biotechnology
Fundamentals and Applications, Third Edition
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Product details:
- Edition number 3, New edition
- Publisher CRC Press
- Date of Publication 30 October 2007
- ISBN 9781420044379
- Binding Paperback
- No. of pages512 pages
- Size 280x210 mm
- Weight 950 g
- Language English
- Illustrations 48 Illustrations, black & white; 161 Illustrations, color; 18 Halftones, black & white; 82 Tables, black & white 0
Categories
Short description:
Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the regulatory issues factoring into the biopharmaceutical approval process
Setting the standard for biopharmaceutical education in the 21st century, this title discusses general concepts in the production and clinical pharmacology of monoclonal antibodies, as well as their therapeutic application in cancer treatment, immunosuppressive therapy related to organ transplantation, and anti-inflammatory therapy?describes regulatory requirements of biotechnology drug products to receive approval to market?presents challenges and approaches for overcoming an undesired immune response to protein therapeutics?addresses the discovery and clinical development of the new biotechnology-produced drugs
Long description:
Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, administration, and therapeutic developments. New chapters cover evolving areas regarding biopharmaceuticals, including oligonucleotides, siRNA and various monoclonal antibodies, immunogenicity, gene therapy, and the regulatory issues factoring into the biopharmaceutical approval process
MoreTable of Contents:
Molecular Biotechnology. Biophysical and Biochemical Analysis of Recombinant Protein Structure and Analysis of Proteins. Production and Downstream Processing of Biotech Products. Formulation of Biotech Products, Including Biopharmaceutical Considerations. Pharmacokinetics and Pharmacodynamics of Peptide and Protein Drugs. Immunogenicity. Genomics, Proteomics and Additional Biotechnology-related Techniques. Gene Therapy. Oligonucleotides and siRNA. Hematopoetic Growth Factors. Interferons and Interleukins. Insulins. Growth Hormones. Recombinant Thrombolytics and Coagulation Factors. General Considerations of Monoclonal Antibodies. Monoclonal Antibodies in Oncology. Monoclonal Antibodies in Transplantation. Monoclonal Antibodies in Anti-inflammatory Therapy. Recombinant Human Deoxyribonuclease. Follicle-stimulating Hormone. Vaccines. Dispensing Biotechnology Products. Economic Considerations in Medical Biotechnology. Regulatory Issues and Drug Product Approval for Biopharmaceuticals
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