| ISBN13: | 9780323918183 |
| ISBN10: | 0323918182 |
| Binding: | Paperback |
| No. of pages: | 486 pages |
| Size: | 276x215 mm |
| Weight: | 1330 g |
| Language: | English |
| 662 |
Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics
EUR 175.00
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Physico-Chemical Aspects of Dosage Forms and Biopharmaceutics: Recent and Future Trends in Pharmaceutics, Volume Two explores aspects of pharmaceutics with an original approach that focuses on technology, novelties and future trends. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day, so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. Readers will find practical information for conducting research in pharmaceutics that is ideal for researchers in academia and industry as well as advanced graduate students in pharmaceutics. In addition, the book discusses the most recent developments in biopharmaceutics, including important and exciting areas such as solubility of drugs, pharmaceutical granulation, routes of drug administration, drug absorption, bioavailability and bioequivalence.
Section I: Physico-chemical aspects of dosage forms 1. Physico-chemical factors influencing drug degradation 2. Stability and accelerated stability studies of dosage forms 3. Solubility of drugs 4. Drug dissolution studies of pharmaceutical formulations 5. Pharmaceutical granulation: Engineering perspective and futuristic trends 6. Tablet compression and consolidation: Theory and applications Section II: Biopharmaceutics 7. Introduction to Biopharmaceutics 8. Gastrointestinal absorption of drugs 9. Routes of drug administration and their impact in biopharmaceutics 10. Drug elimination and renal excretion of drugs 11. Membrane transport and permeation of drugs 12. Factors affecting drug absorption and disposition 13. Bioavailability and bioequivalence 14. Contribution of biopharmaceutics and pharmacokinetics to improve drug therapy 15. Dosage regimen 16. Multicompartment models 17. Nonlinear pharmacokinetics 18. Computer-aided biopharmaceutical model development 19. Computer simulations in pharmacokinetics 20. WHO and ICH Guidelines for ‘Good Manufacturing Practices’ 21. Pilot plant scale up techniques in pharmaceutical product development 22. Advances in solid dosage forms