ISBN13: | 9780443137747 |
ISBN10: | 0443137749 |
Binding: | Paperback |
No. of pages: | 854 pages |
Size: | 229x152 mm |
Language: | English |
700 |
Polymers for Oral Drug Delivery Technologies
EUR 235.00
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Polymers play an important role to achieve the targeted release profile consistently of an API in vivo by various functionalities like drug protection from gastric juice, fast release and supersaturation or release within a targeted area of the GI tract.
- Provides a comprehensive update on the state of polymer technology for oral drug delivery, bringing the reader up-to-speed via a single reference
- Covers a range of polymer technology types, including capsule forming polymers, matrix formers, functional polymer coatings, and more
- Contains contributions from global experts spanning academia and industry, offering an interdisciplinary and translational approach to polymers for oral drug delivery
Section A. Fundamentals of Oral Drug Delivery 1. GI tract environment (e.g. gastric juice, bile salts, pH, amylases, proteases etc.) 2. GI tract motility and transport 3. Drug absorption and pre-systemic metabolism and PK modelling 4. In vitro dissolution and predictive release testing 5. Principle characteristics and specification of pharmaceutical polymers 6. Regulatory Aspects of Polymers Used and new polymers for Oral Medication Section B. Role Polymer Technology in Oral Drug Delivery 7. Classes/types of polymers used in oral delivery (natural, semi-synthetic, synthetic), their chemical structure and general functionalities 8. Role of polymers in Tableting 9. Capsule forming Polymers 10. Dry and wet Granulation 11. Matrix formers 12. Functional Polymer Coatings (IR, easy to swallow, enteric etc.) 13. Amorphous systems (e.g. HME, SD) 14. Micro/Nanoparticles 15. Taste masking polymers 16. Polymers in Orally disintegrating tablets and Orally dissolving films 17. Additive manufacturing (3D printing) 18. Mucoadhesive forms 19. Gastro-retentive forms 20. Polymer blends and additives