
Recent Advances in Electron Cryomicroscopy, Part A
Series: Advances in Protein Chemistry and Structural Biology; 81;
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- Discounted price 52 304 Ft (49 813 Ft + 5% VAT)
58 115 Ft
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Product details:
- Publisher Academic Press
- Date of Publication 24 December 2010
- ISBN 9780123813572
- Binding Hardback
- No. of pages144 pages
- Size 228x152 mm
- Weight 400 g
- Language English 0
Categories
Long description:
Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.
While most structural biologists pursue structures of individual proteins or protein groups, specialists in structural genomics pursue structures of proteins on a genome wide scale. This implies large-scale cloning, expression and purification. One main advantage of this approach is economy of scale.
MoreTable of Contents:
- From envelopes to atoms: the remarkable progress of biological electron microscopy
- Single-particle applications at intermediate resolution
- Visualizing molecular machines in action: single particle analysis with structural variability
- Cellular Tomography
R. Anthony Crowther
Bettina Böttcher and Katharina Hipp
Sjors H.W. Scheres
Andreas Hoenger and Cédric Bouchet-Marquis
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