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    The Handbook of Dopamine
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      • Publisher's listprice EUR 232.99
      • The price is estimated because at the time of ordering we do not know what conversion rates will apply to HUF / product currency when the book arrives. In case HUF is weaker, the price increases slightly, in case HUF is stronger, the price goes lower slightly.

        98 834 Ft (94 127 Ft + 5% VAT)
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    98 834 Ft

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    Product details:

    • Publisher Academic Press
    • Date of Publication 5 May 2025

    • ISBN 9780443298677
    • Binding Hardback
    • No. of pages820 pages
    • Size 276x216 mm
    • Language English
    • 700

    Categories

    Long description:

    The Handbook of Dopamine captures current understanding of dopamine biology in the brain, including anatomical organization of dopamine neurons, their molecular and genetic diversity, synaptic and circuit connectivity, receptor function and signalling, through to diverse roles in behaviors and finally, dysfunction in disease. This volume compiles a comprehensive set of perspectives from a large number of leading scientists working in dopamine research. The volume describes the current state-of-the-field, summarizing knowledge that has been transformed in the last decade through the advent and application of sophisticated new technologies.


    • Offers up-to-date review of dopamine biology across fields
    • Explores the function and regulation of dopamine neurons in healthy behavior and also dysfunction in disease
    • Includes historical and future perspectives in the field of dopamine research

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    Table of Contents:

    Introduction: A general perspective on dopamine

    Section 1: Molecular neuroanatomy of dopamine neurons: Development, diversity and connectivity
    1. The dopamine system in an evolutionary perspective
    2. Molecular heterogeneity of midbrain dopamine neurons
    3. Building an action circuit with nigrostriatal dopaminergic neurons and striatonigral neurons
    4. Anatomy of dopamine neuron projections: AXONAL arbours, varicosities, and synapses
    5. DA neuron connectomes: Inputs and outputs

    Section 2: Dopamine neuron physiology and dopamine release regulation
    6. Electrical patterns of activity in dopamine midbrain neurons {i|in vivo}
    7. Computational modeling of midbrain dopamine neurons
    8. Axonal DA release: Molecular mechanisms
    9. Somatodendritic DA release
    10. Regulation of dopamine transmission by striatal neuromodulators
    11. DA transporters and the nanoscale organisation of the DA axon
    12. Beyond DA: Co-transmission by DA neurons

    Section 3: Dopamine signalling: receptors, postsynaptic integration and plasticity
    13. Unveiling Activation Mechanisms and Intrinsic Divergence of the Dopamine Receptors Based on Experimentally Determined Structures
    14. DA receptor drugs and their applications
    15. Postsynaptic integration and plasticity in the striatum
    16. DA signalling roles in the extrastriatal basal ganglia
    17. Postsynaptic integration and plasticity in prefrontal cortex

    Section 4: Dopamine mechanisms of learning and reinforcement
    18. The dopamine reward prediction error signal
    19. Diversity of encoding: Reward to aversion
    20. Dopamine beyond temporal-difference reinforcement learning
    21. Habits and dopamine
    22. Dopamine for performance evaluation - insights from songbirds
    23. Striking parallels between the dopaminergic systems of flies and mammals
    24. Computing with dopamine: a convergence of natural and artificial intelligence
    Section 5: Dopamine function in motivated behaviour
    25. Dopamine and the temporal control of behavior
    26. Volition and vigour
    27. Effort and activation
    28. Exploration and behavioral variability
    29. Role of dopamine in adaptively tuning motivational bias to the current environment
    30. Sex differences in Dopamine Systems involved in Motivation and Reward
    31. Dopamine and appetite

    Section 6: Dopamine dysregulation: from neurology to psychiatry
    32. Neuronal design and determinants of selective neuronal vulnerability of dopaminergic neurons in Parkinson’s disease
    33. Understanding human dopamine neuron biology in Parkinson's patient cells
    34. Dopamine replacement for Parkinson's disease: clinical approaches and experimental underpinnings
    35. Dopamine modulation of synaptic transmission in drug addiction
    36. Molecular Reprogramming of D1 and D2 Dopaminoceptive Medium Spiny Neurons in Substance Use Disorder
    37. Human DA systems in addiction disorders
    38. Apathy and Impulsivity in Neurological and Psychiatric disorders
    39. Dopamine dysfunction in psychosis
    40. Dopamine systems in impulsive-compulsive behaviour

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    The Handbook of Dopamine

    The Handbook of Dopamine

    Cragg, Stephanie J.; Walton, Mark; (ed.)

    98 834 HUF

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