Handbook of Proteases in Cancer

I.               General Aspects

1.1.          Influence of Serine Proteases on Bone Morphogenetic Proteins: Insights for Advancing Treatment Paradigms in Breast Cancer

          Anmol Kapoor, Chandi C. Mandal

1.2.  Proteases in Cancer Theranostics

Deepmala Karmakar, Sanghamitra Sengupta

1.3.         Structural aspects of proteases in cancer therapeutics: A perspective

 Anirban Nandy, Sima Biswas, Angshuman Bagchi

II.            Proteases in Cancer Therapy

2.1 Ubiquitin specific proteases: The role and potential in cancer immunotherapy

Bee Ling Tan¹, Ayman El-Meghawry El-Kenawy^2,3, Yin Sim Tor⁴

2.2. Proteasome, the recycle bin of the cancer cell

Amy Dunne Miller¹, Vasudha Tandon¹, Nilabja Sikdar², Sourav Banerjee¹

2.3. The role of caspase 3 in post chemotherapy breast and colorectal cancer relapse and metastasis.

Andreja Leskovac, Sandra Petrovic

2.4. Role of Serine Proteases in Gastric Cancer: Inhibition and Cure

 Reena Kumari^1,2, Kshetrimayum Birla Singh², Amit Kumar Rai¹,

Sivakumar Vijayaraghavalu^2*

2.5. Serine protease inhibitors in breast cancer therapy

Abinaya Elango, Arunkumar Radhakrishnan*

2.6. Serine proteases in cancer: Mechanisms and treatment options

Madhu Tanya Singh; Ammu V. V. V. Ravi Kiran; Garikapati Kusuma Kumari; Praveen T. Krishnamurthy*

2.7. Survivin, a moonlighting caspase inhibitor and potential oncotherapeutic target
Abdul Basit Baba¹, Rajakishore Mishra², Siddavaram Nagini³

2.8. Ubiquitin-specific proteases for the treatment of breast cancer

Suchetana Pal¹, Subhasish Sarkar², Rajlakshmi Laha², Somasri Dam

2.9. Microbial secretory proteases: a new insight in the field of cancer therapies

 Nanda Singh, Rima Tapader, Amit Pal

2.10. The emerging role of the ?-secretase inhibitors in cancer management

 Anuj Kumar Borah¹, Chongtham Sovachandra Singh¹, Babiangshisha Kharbuli¹, Anupam Chatterjee², Subhendu Chakrabarty³, Amlan Das¹

2.11. Cathepsins in cancer therapy and precision medicine

Namrata Singh^1*, Aqsa Khan², Asma Mohin Rojewale¹, Shinjinee Sengupta²

2.12. The Emerging Role of Calpain 2 Protease as a Therapeutic Target in

Breast Cancer

Praveen Kumar Chandra Sekar¹, Jayakumar Subramaniyan², Ramakrishnan Veerabathiran^1*

III.            Epigenetic Tools and Stem Cell Therapy

3.1. Calpains, miRNA and cancer: an overview

Sajal Chakraborti¹*, Mahasweta Ghosh¹, Rajabrata Bhuyan², Dibyapriya Roy Chowdhury¹, Tapati Chakraborti¹  

3.2. The roles of ubiquitin-specific proteases (USPs) in cancer stem cell maintenance.

Kuan Ping Anga², Won Fen Wonga³, Chung Yeng Looi

3.3. Modulatory Effects of Stem Cell Therapy on Cysteine Proteases and Matrix Metaloproteases in Breast Cancer

 Nour Y. S. Yassin, Noha A. Ahmed, Manal N. Abdel Azeem, Osama M. Ahmed

3.4. Application of metalloproteases in cancer stem cell therapy

Uju Dorathy Iliemene¹*, Paul T. Olonishuwa¹, and Mubarak Labaran Liman²

3.5. Regulatory Mechanisms and Clinical Potential of Epigenetic Targeting in Glioma

Yetirajam Rajesh, Suvendu Nandi, Priya Ghosh, Mahitosh Mandal*

3.6. Associations of proteases and long non-coding RNAs in cancer

Gaurav Kumar Bhagat¹, Dipanjan Guha², Angshuman Bagchi

3.7. Stem cell-mediated interventions in cancers caused by proteases

Farheen Showkata², Sabra Parveena², Neetu Badesraa², Mohmmad Saleem Dar^1,2, Md Mehedi Hossaina², Mir Owais Ayaz^1,2, Mohd Jamal Dar^1,2

3.8. Stem cell therapy in bone marrow cancer

Arjun K R, Girish Kanavi K, Sudipta Choudhury, Mythreyi R, Kanthesh M Basalingappa

IV.           Nanotechnology Based Therapies

4.1. Protease-targeting nanoparticles for cancer therapy and imaging

Sandra Petrovic*, Andreja Leskovac

4.2. Nanomedicine role in proteolytic landscape of breast cancer

Sobia Noreen¹, Mehwish Ishtiaq¹, Sara Hasan^1,2, Shazia Akram Ghumman³, Samina Aslam⁴

4.3.  Proteasome Inhibitors and Nano-Delivery Systems for Therapy of Glioblastoma Multiforme

Mekala Janaki Ramaiah¹, Sahiti Chamarthy¹, Janumala Mary Edna¹, Katari Sukeerthi², Nallapaty Srilakshmi², Prasanna Srinivasan Ramalingam³, Sivakumar Armugam³

4.4. Emerging proteases for molecular imaging and therapy in cancer

Presenjit^1,2, Shubhra Chaturvedi¹, Vishaka Chaudhary^1,3, V.P. Singh⁴, Kaman Singh², A.K. Mishra^1*

4.5. Novel nano technologies associated with Car-T cell therapy in breast cancer

 Avipsa Hazra¹, Ragini Khanna², Parthiban R³, Gopenath TS⁴,

Kanthesh BM^1*

V.              Bioinformatics and System Biology

5.1. System biology approach of protease Cathepsin K in glioblastoma multiforme

Prasanna Srinivasan Ramalingam1, Sivakumar Arumugam1, Purushothaman Balakrishnan2, Janaki Ramaiah Mekala

5.2. Omics technologies for matrix metalloproteinases: MMPs as cancer biomarkers

Sherlin Rosita Arockiaraj¹, Jay Shree Mathivanan¹, Shivani Jambulingam¹, Karnati Balaji², Mahima Bhardwaj², Pushparaj Annadurai³, Thomas Jebastin¹, Abhinav Parashar⁴, Daniel A. Gideon^5*

5.3. Designing Novel Serine Protease Inhibitors against Potential Biomarkers specific to Lung Adenocarcinoma through Systems Biology and Structural Bioinformatics Approaches

Anamika Mishra¹, Aniket Naha²*, Soundharya H¹, Soumitra Nath³*, Nibu Varghese⁴, Soumya R S⁵

5.4.  System biology and bioinformatics approaches in HTLV-1 protease targeting adult T-cell leukemia disease

Chandrabose Selvaraj¹, Sanjeev Kumar Singh², Devadasan Velmurugan

5.5. Protease profiling in lung cancer using bioinformatics tools

Protease Profiling in Lung Cancer using Bioinformatics Tools

Gowrav Baradwaj, Avipsa Hazra, Dhanu AS and Kanthesh M Basalingappa