Human and Animal Relationships by Brakhage, Axel A.; Kniemeyer, Olaf; Zipfel, Peter F.;

Hosszú leírás:

Estimates based on sequencing data suggest that there are around 5.1 million species of fungi. Yet only a small number of fungi are harmful to animals, including humans. In addition to host-pathogen interactions, there are also mutualistic interactions between fungi and animals. Diseases caused by pathogenic fungi range from allergic reactions and superficial infections to invasive mycoses, and have a significant impact on human and animal life. Fungi are also cultivated by animals as a food source in highly developed relationships or are even involved in gut mutualism.

This 3rd edition of Volume 6 of The Mycota highlights exemplary interactions between fungal pathogens and their host(s). The book is organized in three parts:

• Part 1 summarizes our current understanding of important pathogenic fungi such as Candida species, Malassezia yeasts, Aspergillus fumigatus and fungi of the order Mucorales.
• Part 2 addresses the characterization of the host response towards pathogenic fungi. It focuses on RNA as a mediator of host-pathogen interactions, the human gut mycobiome, the role of the innate immune system in fighting infections, pattern recognition receptors involved in fungal infections, and a summary of established infection models for studying host-fungal-pathogen interactions.
• Part 3 provides insights into the impact transcriptomics and proteomics technologies have on the research of human-pathogenic fungi.

The up-to-date reviews by experts in the field provide the reader with a comprehensive overview of the various research topics in the field of human and animal relationships with fungi and will hopefully help researchers to find inspiration for their own research.

Tartalomjegyzék:

Part I. Pathogens.- Chapter 1. Trinity of Environment, Animals, and Humans: A Résumé in the Case of the Fungal Order Mucorales.- Chapter 2. Pathogenicity Strategies of Candida Species During Interaction with Epithelial Cells.- Chapter 3. Malassezia Yeasts in Animals in the Next-Generation Sequencing Era.- Chapter 4. Extracellular Proteins and Their Roles in Aspergillus Fumigatus Pathogenesis.- Part II. Host-Pathogen Interaction.- Chapter 5. RNA as a Mediator of Host-Fungal Pathogenesis.- Chapter 6. The Human Gut Mycobiome and Its Potential as a Regulator of the Host’s Metabolic Health.- Chapter 7. The Host Innate Immune Response to Pathogenic Candida Albicans and Other Fungal Pathogens.- Chapter 8. Mammalian Pattern Recognition Receptors (Prrs) Involved in Recognition of Fungi.- Chapter 9. Infection Models for Human Pathogenic Fungi.- Part III. Techniques.- Chapter 10. Transcriptomic Analyses of Host Colonisation in Fungal Pathogens of Humans.- Chapter 11. Proteomics and Its Application to the Human-Pathogenic Fungus Aspergillus Fumigatus.